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Clinical Trials

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HUMAN CLINICAL STUDIES – JOINT HEALTH

Effect of BioCell Collagen®, on Improving Joint Comfort: A Randomized, Double-Blind, Placebo-Controlled Trial
  • Eighty subjects were divided into two groups and administered either 2 g of BioCell Collagen® supplement or placebo for ten weeks.

  • Compared to placebo, the BioCell group had a significant improvement of joint comfort on days 35 (p = 0.017) and 70 (p < 0.001).

  • BioCell group experienced a significant improvement in physical activities compared to the placebo group on days 35 (p = 0.007) and 70 (p < 0.001).

  • BioCell Collagen was well tolerated and found to be effective, thereby improving mobility and quality of life.

The peer-reviewed study was published in the Journal of Agriculture and Food Chemistry. (https://pubs.acs.org/doi/10.1021/jf205295u) (Schauss et al., 2012).

Results of study – Min. 30% improvement in 71% of subjects taking BioCell Collagen

HUMAN CLINICAL STUDIES – JOINT HEALTH

A Randomized Double-Blind Clinical Pilot Trial Evaluating the Safety and Efficacy of BioCell Collagen® in Adults for Joint Comfort
  • Sixteen subjects split evenly into two groups, ingested 1000 mg of BioCell Collagen® twice daily (2g) or placebo for eight weeks.

  • As compared to the placebo group, the BioCell group showed a 40% improvement in WOMAC pain scores.

  • No adverse events associated with BioCell Collagen.


The study details were presented at the international conference of Experimental Biology, 2004, Washington, DC.

Results of this pilot study: 40% improvement in WOMAC pain scores

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HUMAN CLINICAL STUDIES – JOINT HEALTH

BioCell Supplement on Subjective Discomfort (1999)
  • This 89 subject, prospective, crossover double-blind clinical study compared 2 g daily supplementation of the BioCell ingredient versus placebo over three months.

  • Out of the 89 participants who complained of subjective discomfort of various types, 80 of them (89%) reported some level of improvement within 45 days of taking the BioCell supplement.

  • In contrast, only one subject on placebo had improved.

  • No adverse events with the BioCell supplement. (1999 unpublished study)


Results of study – Effective in 89% of subjects




HUMAN CLINICAL STUDIES – BEAUTY FROM WITHIN

BioCell Collagen® Improves Facial Epidermis and Connective Tissue in Healthy Adult Females: A Randomized, Double-Blind, Placebo-Controlled Trial.

One hundred thirteen healthy female subjects aged 39 to 59 years.

  • Subjects ingested 1 g of BioCell Collagen® daily in two equally divided doses, morning and evening for 12 weeks.

  • BioCell Collagen® demonstrated the following results compared to a placebo:

    • Significantly reduced facial lines and wrinkles (P = .019) and crow’s feet lines and wrinkles (P = .05)

    • Significantly increased skin elasticity (P = .008) and cutaneous collagen content (P < .001) by 12%

    • Significantly improved indicators associated with a more youthful skin appearance based on visual grading and wrinkle width (P = .046)

    • Decreased skin dryness and erythema

    The study findings are published in the journal of Alternative Therapies in Health and Medicine (2019).
    (https://www.ncbi.nlm.nih.gov/pubmed/31221944)

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HUMAN CLINICAL STUDIES – BEAUTY FROM WITHIN

Ingestion of BioCell Collagen®; enhanced blood microcirculation and reduced facial aging signs.
  • Twenty-six healthy female subjects aged 35 to 59 years of various ethnic origin.

  • Subjects ingested 1 g of BioCell Collagen® daily in two equally divided doses, morning and evening for 12 weeks.

  • BioCell Collagen® demonstrated the following results:

    • Significant reduction of facial lines and wrinkles

    • Significant reduction of facial skin dryness and scaling

    • Significant increase in facial dermal collagen content and microcirculation

    The study findings are published in the journal of Clinical Interventions in Aging (2012).
    (http://www.ncbi.nlm.nih.gov/pubmed/22956862)

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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

© 2026 BioCell Technology, LLC. All Rights Reserved. BioCell Collagen™ is a trademark of BioCell Technology, LLC, registered in the United States and other jurisdictions.

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Stay updated with our newsletter
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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

© 2026 BioCell Technology, LLC. All Rights Reserved. BioCell Collagen™ is a trademark of BioCell Technology, LLC, registered in the United States and other jurisdictions.

Brand
Stay updated with our newsletter
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*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

© 2026 BioCell Technology, LLC. All Rights Reserved. BioCell Collagen™ is a trademark of BioCell Technology, LLC, registered in the United States and other jurisdictions.

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